CJC 1295 w DAC (5mg)
$60.00
CJC-1295 with DAC (Drug Affinity Complex) is a synthetic analog of growth hormone-releasing hormone (GHRH) engineered for extended activity through albumin binding. Research has explored its potential to sustain growth hormone secretion, influence IGF-1 production, and enhance metabolic regulation. The DAC modification provides a longer half-life compared to standard CJC-1295, making it a valuable subject for studies focused on peptide stability and endocrine modulation.
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Introduction
CJC-1295 with DAC (Drug Affinity Complex) is an advanced derivative of the original CJC-1295 peptide. The inclusion of DAC technology allows the molecule to bind to serum albumin, greatly extending its biological half-life. This feature enables prolonged stimulation of growth hormone release and insulin-like growth factor 1 (IGF-1) production, making it of significant interest in endocrine and metabolic research. Experimental studies have also evaluated its potential applications in tissue maintenance, energy metabolism, and age-related hormone regulation.
Stability and Bioavailability
The DAC modification enhances the stability and duration of CJC-1295’s biological activity. By forming a covalent bond with plasma proteins, the peptide resists rapid enzymatic degradation and maintains sustained presence in the bloodstream during research trials. Its prolonged half-life—reported to last up to several days in experimental models—makes it an optimal choice for studying chronic peptide signaling and controlled hormone release kinetics.
Research Applications
Growth Hormone and IGF-1 Regulation
CJC-1295 w/ DAC has been shown in research settings to increase pulsatile growth hormone secretion and subsequently elevate IGF-1 levels. This regulated mechanism provides a framework for studying peptide-mediated endocrine feedback and metabolic adaptation.
Metabolic Function and Cellular Regeneration
Through its impact on GH and IGF-1 pathways, CJC-1295 w/ DAC may play a role in energy expenditure, protein synthesis, and cellular recovery processes in experimental models. Studies suggest long-term modulation of anabolic activity and improved metabolic function.
Peptide Pharmacokinetics Research
The extended duration of action provided by DAC technology makes CJC-1295 w/ DAC an ideal candidate for studying long-acting peptide formulations and sustained-release systems. Researchers often use it as a reference peptide for developing future analogs with improved pharmacodynamics.
Summary
CJC-1295 w/ DAC stands out as a model peptide for long-acting growth hormone modulation research. Its extended bioavailability and stable pharmacokinetic profile make it well-suited for studies of metabolic regulation, endocrine balance, and tissue recovery processes. Continued research on CJC-1295 w/ DAC contributes to a better understanding of peptide-based hormone regulation strategies in laboratory settings.
References
- Teichman SL et al., Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I (IGF-I) secretion by CJC-1295, a long-acting GHRH analog, Journal of Clinical Endocrinology & Metabolism (2006). PubMed
- Sackmann-Sala L et al., CJC-1295 with drug affinity complex: Enhanced half-life and GH/IGF-1 modulation in clinical studies, European Journal of Endocrinology (2009). PubMed
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Strasburger CJ et al., Development of growth hormone secretagogues, Endocrine Reviews (2005). PubMed
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body.
These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease.
Bodily introduction of any kind into humans or animals is strictly forbidden by law.
Storage Instructions
All peptides are manufactured using lyophilization (freeze-drying), a process that protects product integrity during shipping and storage. This ensures that peptides remain stable for 3–4 months while in their lyophilized form.
Once reconstituted (mixed with bacteriostatic water), peptides should be stored in the refrigerator and will remain stable for up to 30 days.
Lyophilized peptides (unmixed powder) can be kept at room temperature for short-term storage but should ideally be refrigerated under 4°C (39°F) to maintain stability. For long-term preservation (several months to years), peptides should be stored in a freezer at -20°C to -80°C (-4°F to -112°F).
Proper storage helps maintain purity and quality, ensuring your peptides are reliable for research use.
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